Center for Protein Structure and Function – 2008 Symposium
May 15, 2008 – Chemistry Building
Schedule of Events
8:30 a.m. Talks (CHEM 144)
10:15 a.m. Poster Session (CHEM 105, CHEM 118)
1:30 p.m. Talks (CHEM 144)
2:45 p.m. Poster Session (CHEM 105, CHEM 118)
4 p.m. Round Table Discussion (Harrison Hale Lounge - CHEM 220) Faculty and Advisory Committee
Symposium is open to the public
Morning Talks (CHEM 144)
8:30 a.m. Frank Millett, overview of the Center for Protein, Structure and Function
8:40 a.m. Julie Stenken “Microdialysis Sampling for in Vivo Collection of Proteins and Peptides”
9:15 a.m. Paul Adams “Biophysical Approaches to Characterize the Molecular Basis of Abnormal Cell Signaling Function Involving Ras-Related Proteins”
9:50 a.m. David Bateman “Lead Discovery through Natural Products Total Synthesis”
1:30 p.m. Yuchun Du “Quantitative Proteomic Analysis of Protein Complex, Protein Expression, and Protein Phosphorylation”
2:05 p.m. Vitaly Vostrikov “Use of Solid-State NMR to Measure the Tilt of Transmembrane Helices in Mixed Lipid Systems”
2:25 p.m. Karuppanan Kathir “Understanding the Mechanism of the Anti-angiogenic Activity of Suramin”
Morning Poster Session
(CHEM 105, CHEM 118) 10:15 a.m.
1. Anna E. Daily, D. Rajalingam, T. K. S. Kumar “Role of Annexin in the Non-Classical Secretion of Signal Peptide-less Proteins”
3. Raja Dakshinamurthy, T. K. S. Kumar “Biophysical Characterization of Human Interleukin-1 alpha”
5. Koteshwara Ananthamurthy, K. M. Kathir, R. Goforth, R. Henry and T. K. S. Kumar “The Three-dimensional Solution Structure of the C-terminal chromodomain of the 43 kDa Subunit of the Chloroplast Signal Recognition Particle”
7. Lindsay Rutherford, D. Rajalingam and T. K. S. Kumar “Understanding the Molecular Mechanism Underlying the Auto Inhibition of the Fibroblast Growth Factor Signaling”
9. Nicole Webb, D. Rajalingam, Denise Greathouse, and T. K. S Kumar “Specificity of the Helical Conformation Induced by 2, 2, 2, Trifluoroethanol”
11. Ryan Thurman, D. Rajalingam, F. Guo, J. Sakon, T. K. S. Kumar “Understanding the Stability of the D2 Domain of the Fibroblast Growth Factor Receptor”
13. Michelle Munro “Mapping Functional Domains of Basigin and Identifying Basigin Interacting Proteins”
15. Fei Guo “2:2:2 FGF:FGFR:Heparin Complex”
17. Leena Philominathan “The Role of CBD in Collagen Fibril Disruption”
19. Rachel Ellis, Denise Greathouse “Effect of Linker on Transmembrane Peptide-Anchored Lactoferricins in Neutral and Anionic Lipids”
21. Nicole McClellan, T. K. S. Kumar, D. Rajalingam, and Denise Greathouse “Molecular Interactions of Lactoferricin Peptides”
23. Chris Mazzanti “Structural Studies of the Transmembrane and Cytoplasmic Domains of Anthrax Toxin Receptor”
25. Jianhong Zhou, Yuchun Du “Isolation of Intact Endogenous ATM Protein Complexes from Mammalian Cells”
27. Naomi J. Marty, D. Rajalingam, A. D. Kight, N. E. Lewis, D. Fologea, T. K. S. Kumar, R. A. Henry, R. L. Goforth “Role of a Membrane-activated Structural Switch Mechanism in Chloroplast SRP Receptor Function”
29. Nathaniel E. Lewis, N. J. Marty, D. Rajalingam, A. D. Kight, T. K. S. Kumar, R. L. Henry, R. L. Goforth “Interactions With the Translocon in Signal Recognition Particle Protein Targeting”
31. David Clay and Juliette Rivero, M. McIntosh “Toward the Synthesis of Antascomicin B. Synthesis of the C22-C34 and C10-C16 Fragments via Ireland-Claisen and Allylic Diazene Rearrangements”
33. Lauren Blair “Utility of Electron Transfer Dissociation in a Linear Ion Trap for the Mass Spectrometric Analysis Of Histone H3”
35. Zeeshan Kamal, M. McIntosh “Functionalization and Applications of Magnetic Nanoparticles: From Separation Science to Drug Delivery”
Afternoon Poster Session
(CHEM 105, CHEM 118) 2:45 p.m.
2. Anne Froyd-Rankenberg “Investigation of “Half-WALP” Peptides in Presence of Model Membrane Lipids using 2H and 31P NMR Spectroscopy”
4. Jennifer Diaz Lemmons “Structure and Dynamics of the Gramicidin A Channel”
6. Jeff Froude “Isolation of Thrombomodulin from Human Urine and Characterization of Met-388 Oxidation Status”
8. Chris Saunders “Development of Methods to Alkylate Methionine”
10. Alan Tackett “Saccharomyces Cerevisiae Yta7 Regulates Histone Gene Expression”
12. Venkat Laxmi Yeruva, “Investigation of NS3h Translocation, Unwinding and, Protein Displacement along the DNA”
14. Lauren Blair “Structural Studies of Bacteriophage T4 Helicase Dda”
16. Maha L. Shrestha and Wei Qi, M. McIntosh “New Applications of Allylic Diazene Rearrangement”
18. Huimin Liu “Expression of, and Preliminary Biophysical Characterization of a Minimal Binding Domain peptide of TSC2 that binds to the small GTPase Rheb”
20. Emily Edwards “An Innovative Method For the Purification of Recombinant Proteins”
22. Kwangyul Moon, K. M. Kathir, K. Ibrahim, R. E. Gawley and T. K. S. Kumar “Understanding the Mechanism of the Anti-angiogenic Activity of Suramin”
24. Penny Lewis “Progress Toward a Microelectrochemical Sensor for Saxitoxin using Saxiphilin c-lobe”
26. Dan Eddings “New Chiral Cu(I)-NHC Catalyst for Asymmetric Cyclopropanations”
28. Ryan Farris “Synthesis and Quartz Surface Modification of 9,10-di-subsituted-anthracene 18-crown-6 Chemosensors for the Detection of Saxitoxin”
30. Susan Grisham “Super-Paramagnetic Nanocrystal with Second Generation >Dendron Ligand Suitable for Catalytic Application”
32. Sandra Schmitt, Yanling Liu, Angeline Gradolatto, Alan J. Tackett, and Michael Lehmann “Identification of Novel Interaction Partners of the Chromatin-Associated Protein Pipsqueak”
34. Vitaly Vostrikov “Properties of WALP23 in Mixtures of Oriented Lipids Investigated by Solid-State 2H and 31P NMR Spectroscopy”